Rejected at 2:14 a.m. Nov, 01, 2023 ] by Ahmed7
Bulk Suggestion Bulk ID: skstroh/04.01.23-02:57PM
Author: skstroh
Related Note: 1478995078338
Rationale for change

Removed UW tag that didn't match content

Text
Paroxysmal nocturnal hemoglobinuria (PNH) may be treated with {{c1::eculizumab}}, which is a terminal complement inhibitor
Extra
- Monoclonal antibody for C5 complement protein
- C5 is an important step in generating the membrane attack complex (MAC), formed of C5b + C6-C9
- Causes an increased risk of encapsulated bacterial infections
Lecture Notes
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Missed Questions
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Pathoma
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Boards and Beyond
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First Aid

Sketchy
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Sketchy 2






Watch Intravascular Hemolytic Anemia: Non-MAHA DDx
Sketchy Extra
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Picmonic
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Pixorize
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Physeo
Bootcamp
Watch associated Bootcamp video - Paroxysmal Nocturnal Hemoglobinuria

Watch associated Bootcamp video - Complement Disorders
OME

Additional Resources
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One by one
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Changed Tags
#AK_Step1_v12::#UWorld::18594
#AK_Step2_v12::#OME::01_Medicine::05_Hematology_Oncology::04_Normocytic_Anemia #AK_Step2_v12::!Shelf::IM::no_dupes #AK_Step2_v12::Original_decks::Dorian::im::uw::heme/onc #AK_Step1_v12::#AMBOSS::KjaUYk #AK_Step1_v12::#AMBOSS::riafG4 #AK_Step1_v12::#FirstAid::10_Hematology_and_Oncology::04_Pathology::11_Intrinsic_hemolytic_anemias::*Paroxysmal_Nocturnal_Hemoglobinuria #AK_Step1_v12::#Pathoma::05_RBC::06_Normocytic_Anemias_with_Intravascular_Hemolysis #AK_Step2_v12::#Resources_by_rotation::IM::uw::heme/onc::heme/onc_dorian #AK_Step1_v12::#FirstAid::02_Immunology::03_Immune_Responses::05_Complement_disorders::02_Complement_regulatory_protein_deficiencies::*Paroxysmal_Nocturnal_Hemoglobinuria #AK_Step2_v12::#SketchyIM::08_Hematology_&_Oncology::01_Anemia::06_Intravascular_Hemolytic_Anemia_2_Non_MAHA_Ddx !AK_UpdateTags::Step1decks::Zanki-Step-Decks::Zanki-Hematology-&-Oncology::Pathoma-RBC #AK_Step1_v12::#FirstAid::02_Immunology::04_Immunosuppressants::03_Therapeutic_antibodies::01_Autoimmune_disease_therapy::*Eculizumab #AK_Step1_v12::#OME::Clinical::Internal_Medicine::Hematology-Oncology::Normocytic_Anemia #AK_Step2_v12::Original_decks::Dorian::im::ome::heme/onc::normocytic_anemia #AK_Step1_v12::#B&B::11_Hematology::02_Red_Blood_Cells::03_Intrinsic_Hemolysis #AK_Step2_v12::!Shelf::FM::no_dupes #AK_Original_Decks::Step_1::Zanki_Step_Decks::Zanki_Hematology_&_Oncology::Pathoma_RBC #AK_Step1_v12::#FirstAid::02_Immunology::04_Immunosuppressants::03_Therapeutic_antibodies #AK_Step1_v12::#Bootcamp::Immunology::08_Complement::03_Complement_Disorders #AK_Step1_v12::#UWorld::COMLEX::26697 #AK_Step2_v12::#B&B::07_Hematology_and_Oncology::01_Red_Cells::06_Intrinsic_Hemolysis #AK_Step2_v12::#Resources_by_rotation::IM::ome::heme/onc::normocytic_anemia #AK_Step1_v12::#Physeo::^physeo_image_update #AK_Step1_v12::^Systems::HemeOnc::RBC #AK_Step1_v12::#UWorld::Step::18594 #AK_Step2_v12::#Resources_by_rotation::FM::ome::heme/onc::normocytic_anemia #AK_Step1_v12::#Physeo::11_Pathology::10_HemeOnc_Pathology::08_Hemolytic_Anemia_Intrinsic_Causes #AK_Step1_v12::#Bootcamp::Hematology_and_Oncology::04_Normocytic_Anemia::04_Paroxysmal_Nocturnal_Hemoglobinuria #AK_Step2_v12::#AMBOSS::vf0AL2 #AK_Step2_v12::Original_decks::Dorian::fam::ome::heme/onc::normocytic_anemia