Accepted
at 8:33 p.m. Mar, 13, 2025
by
Ahmed7
Author:
bginsy95
Type of change:
New Tags
Rationale for change
uworld qid 18641 - patient takes beta-lactam antibiotic and builds an allergic reaction to it the second time he takes it which would be due to the formation of a hapten carrier protein combination antigens
No changes in fields
Text
Fever, urticaria, and polyarthralgia 1-2 weeks after taking β-lactams or TMP-SMX is suggestive of {{c1::serum sickness-like reaction (SSLR)::diagnosis}}
Extra
- Unlike true serum sickness (type III HSR with immune complex deposition), thought to be caused by hapten-mediated cytotoxicity
- Symptoms resolve completely upon cessation of the offending agent
- Symptoms resolve completely upon cessation of the offending agent
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