Accepted
at 1:37 p.m. Feb, 16, 2025
by
jollydolphin
Author:
jollydolphin
Type of change:
Spelling/Grammar
Rationale for change
sub in subendothelial already means "underlying" in this context so this word is redundant.
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Endothelial cells prevent thrombosis through:
- Thrombomodulin: redirects thrombin to activate protein C, inhibiting factors Va and VIIIa
- tPA: converts plasminogen to plasmin, promoting fibrinolysis
- Prostacyclin (PGI2): inhibits platelet aggregation and causes vasodilation
- Nitric oxide (NO): inhibits platelet adhesion and promotes vasodilation
- Heparan sulfate: enhances antithrombin III, inhibiting thrombin and factor Xa
- Barrier function: blocks exposure to subendothelial collagen and tissue factor
- Thrombomodulin: redirects thrombin to activate protein C, inhibiting factors Va and VIIIa
- tPA: converts plasminogen to plasmin, promoting fibrinolysis
- Prostacyclin (PGI2): inhibits platelet aggregation and causes vasodilation
- Nitric oxide (NO): inhibits platelet adhesion and promotes vasodilation
- Heparan sulfate: enhances antithrombin III, inhibiting thrombin and factor Xa
- Barrier function: blocks exposure to subendothelial collagen and tissue factor
Lecture Notes
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Missed Questions
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Pathoma
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Boards and Beyond
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First Aid
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Sketchy
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Sketchy 2
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Sketchy Extra
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Picmonic
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Pixorize
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Physeo
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Bootcamp
Watch associated Bootcamp video - Coagulation and Fibrinolysis: Coagulation Cascade
Watch associated Bootcamp video - Coagulation and Fibrinolysis: Fibrinolysis and Inhibitors of Hemostasis
Watch associated Bootcamp video - Coagulation and Fibrinolysis: Fibrinolysis and Inhibitors of Hemostasis
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Additional Resources


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