Accepted
at 4:33 p.m. Feb, 04, 2025
by
Ahmed7
Author:
andrewmathias8
Type of change:
Updated content
Rationale for change
Grammar and term specificity
Source: AMBOSS - https://next.amboss.com/us/article/Rk0lnT?utm_source=navbar&utm_medium=anki&utm_campaign=anki&utm_term=neurofibromatosis%2Btype%2Bii&guid=E%2525%255Bfrn6TD4&aid=298bfc66-b119-4c76-b7ef-8bfc7d192ab2&uid=ptfeLeLy0#Z74d7bec525697ad2e0f2d181a4d000fe
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What CNS tumors are associated with neurofibromatosis type II (NF2)?
- {{c1::Meningioma}}
- {{c1::Ependymoma}}
- {{c1::Meningioma}}
- {{c1::Ependymoma}}
Lecture Notes
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Missed Questions
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Pathoma
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Boards and Beyond
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First Aid
Sketchy 2
Watch Primary Brain Tumors in Adults
Watch Primary Brain Tumors in Adults
Sketchy Extra
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Picmonic
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Physeo
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OME
Additional Resources
Atlas:
Ependymal pseudorosette
Photomicrograph of brain tissue (H&E stain)
Tumor cells (cylindrical epithelium) are arranged in a radial manner around several vessels. This pattern is called a perivascular pseudorosette.
Perivascular pseudorosettes are a hallmark of ependymoma.
Ependymoma
Photomicrograph of ependymal tissue (H&E stain)
There is an abnormally high number of cells with round nuclei and abundant cytoplasms. Some cells are arranged in a spoke-and-wheel pattern, surrounding an empty central lumen. Such patterns are called ependymal rosettes (example indicated by green overlay).
Other cells are arranged concentrically around vessels, producing a similar appearance (perivascular pseudorosettes; example indicated yellow overlay).
Other cells are arranged concentrically around vessels, producing a similar appearance (perivascular pseudorosettes; example indicated yellow overlay).
Ependymoma
Cranial MRI (FLAIR-sequence, sagittal view)
A hyperintense, heterogeneous, extended mass is visible on the roof of the 4th ventricle (white outline). At the superior aspect of the tumor, multiple cysts are present (white arrows). As a result of an obstructed circulation of the cerebrospinal fluid, the 3rd ventricle appears widened.
This is a typical radiologic presentation and location of ependymoma.
Atlas:
One by one
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