Rejected
at 6 p.m. Feb, 08, 2025 ]
by
pkaps01
Author:
williamlee11281
Type of change:
Updated content
Rationale for change
negative sense RNA, not DNA has a nucleotide sequence complementary to the mRNA it encodes.
Rejection reason
Thank you very much for your suggestion. DNA has:
Template strand (noncoding, antisense, negative (-) strand)
This strand serves as the template for RNA polymerase during transcription.
The mRNA sequence is complementary to this strand. However you are also correct that this same general concept applies to positive and negative sense RNA.
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The noncoding (antisense/template) strand is the DNA strand that is read by RNA Polymerase II to create mRNA. Therefore, the sequence of the noncoding strand in the 5' to 3' direction is complementary to the mRNA transcript read in the 3' to 5' direction (swapping U for T). 
The coding (sense) strand is the DNA strand that complements the noncoding DNA strand and therefore has the same sequence and directionality as the newly synthesized mRNA (have to switch T with U, though).
The noncoding (antisense/template) strand is the DNA strand that is read by RNA Polymerase II to create mRNA. Therefore, the sequence of the noncoding strand in the 5' to 3' direction is complementary to the mRNA transcript read in the 3' to 5' direction (swapping U for T).
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