We are getting into a pretty nuanced topic here that I think some of the MCAT sources unfortunately do a really poor job of explaining because much of the physiology is beyond the MCAT and they incorporate bits and pieces that dont work together.

For example, Kaplan says Epinephrine is a catecholamine hormone that promotes vasoconstriction in systemic arteries and veins, which would cause a rise in blood pressure. Although it does cause an increase in BP, promoting vasoconstriction in systemic arteries and veins is not entirely true as it promotes vasodilation in the arteries leading to the heart and skeletal muscle as was noted previously by the card and supported by UWorld.

However theres a bunch of problems to fix in this card:

1. First it didn't specifically say that epi causes vasodilation of skeletal muscle. This makes it seem like norepi causes vasodilation which isnt true. Norepi is considered primarily a vasoconstrictor while Epi can have mixed effects. This is addressed in the suggestion.

2. Should we now include an additional bullet that NE causes vasoconstriction?

3. If we are going to include that epi dilates skeletal muscle (as it was included originally), we also need to include that it constricts other vessels and leads to an overall increase in BP. We don't want people to see that it dilates skeletal muscle and then get it confused that it causes a decrease in BP.

4. I'm pretty sure that the book and practice problems only highlight epinephrine as contributing to glycogenolysis. From searching online it seems like NE has some very small contribution though. So makes sense to keep as is? (not add "epinephrine causes...." in front of this?

If we are going to include that epi and NE cause vasodilation of the skeletal muscles we should also be careful to include that it also causes vasoconstriction of other vessels and that overall it increases BP.

Stalled out. Happy to revisit tho