Created at 6:44 p.m. Jan, 28, 2025
Author:
mschlich
Type of change:
Content error
Rationale for change
VMA and HVA are not metanephrines. The 3-O-methylated metabolites of epinephrine (metanephrine) and norepinephrine (normetanephrine) are collectively referred to as metanephrines. Metanephrines are further reduced to VMA. HVA is a dopamine metabolite and is unrelated to metanephrines or their metabolism. When looking for a pheochromocytoma, all three metabolites (metanephrines, VMA, and HVA) can be tested with metanephrines being the most sensitive.
Source: https://next.amboss.com/us/article/Tg06u2?q=pheochromocytoma#Yad8f122589f0e4648f99976996a91646
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