Accepted
at 5:08 p.m. Oct, 31, 2023
by
Alex
Author:
pouroverguy
Type of change:
Content error
Rationale for change
This card implies that the finding of oligoclonal bands is specific for the Dx of MS. This is not true. From UpToDate:
Oligoclonal bands may also be caused by intrathecal production of IgG, and the presence of such bands is a diagnostic criterion for multiple sclerosis [28]. Examples of other diseases that can cause oligoclonal bands in the CSF include infections (eg, nervous system Lyme disease), autoimmune diseases, brain tumors, and lymphoproliferative diseases. Given how many diseases can result in oligoclonal bands in the CSF, the diagnostic utility of this finding is limited.
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