Created at 5:58 a.m. Dec, 07, 2024
Author: antalique
Related Note: 1474165395457 2
Rationale for change

The mnemonic in First Aid 2024 states "Lens has primarily Aldose reductase. Retina, Kidneys, and Schwann cells have only aldose reductase."

The original card states that LARKS stood for all tissues/organs that only have aldose reductase, which is not true. It also listed just "Aldose reductase" for A. This can be misinterpreted as "Aldose reductase is one of the tissues/organs that has only aldose reductase."
Source: Other - First Aid 2024

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Extra
- Thus predisposing to osmotic damage by sorbitol (e.g., cataracts, diabetic retinopathy, and peripheral neuropathy)

- Damage is also caused by NADPH depletion with resultant increased oxidative stress



Lecture Notes
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Missed Questions
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Pathoma
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Boards and Beyond
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First Aid


Sketchy

Watch Diabetes Mellitus Chronic Complications


Watch Metabolism Disorders Fructose Sorbitol
Sketchy 2
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Sketchy Extra
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Picmonic
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Pixorize

Review Sorbitol (Polyol) Pathway
Physeo
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Bootcamp
Watch associated Bootcamp video - Carbohydrates: Sorbitol and the Polyol Pathway
OME

Additional Resources
Atlas:

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#AK_Step1_v12::#B&B::08_Endocrinology::03_Pancreas::02_Diabetes::Extra #AK_Step1_v12::#B&B::03_Biochem::02_Metabolism::06_Fructose_and_Galactose::Extra #AK_Step1_v12::#AMBOSS::#Self_Assessment !AK_UpdateTags::AnKing_Image::Aiman #AK_Original_Decks::Step_1::Zanki_Step_Decks::Zanki_Biochemistry::Metabolism #AK_Step2_v12::Original_decks::Dorian::im::ome::endo::outpatient_dm #AK_Step1_v12::#OME::PreClinical::Endocrine::Endocrine_5:_Pancreas::The_Endocrine_Pancreas #AK_Step1_v12::#Physeo::11_Pathology::02_Endocrine_Pathology::06_Endocrine_Pancreas #AK_Step1_v12::#SketchyBiochem::01_Metabolism::01_Carbohydrates::15_Metabolism_&_Disorders_of_Fructose_&_Sorbitol #AK_Step1_v12::#Pixorize::01_Biochemistry::02_Biochemical_Pathways::13_Sorbitol_(Polyol)_Pathway #AK_Step1_v12::#Bootcamp::Biochemistry::05_Carbohydrates::06_Sorbitol_and_the_Polyol_Pathway #AK_Step2_v12::#Resources_by_rotation::IM::ome::endo::outpatient_dm !AK_UpdateTags::Step1decks::Zanki-Step-Decks::Zanki-Biochemistry::Metabolism #AK_Step1_v12::#FirstAid::01_Biochem::06_Metabolism::20_Sorbitol::*Tissue_Selectivity #AK_Step1_v12::#SketchyPath::07_Endocrine::03_Diabetes::03_Diabetes_Mellitus:_Chronic_Complications #AK_Step2_v12::#B&B::04_Endocrinology::03_Diabetes::02_Diabetes_Complications::Extra #AK_Other::Card_Features::Mnemonic #AK_Other::Card_Features::^One_By_One #AK_Step1_v12::^Systems::Biochem::metabolism::carbs