https://www.uptodate.com/contents/management-of-acute-moderate-and-severe-traumatic-brain-injury

While hуреrvеոtilation can be used to reduce ΙCΡ, particularly in the setting of cerebral herniation, guidelines recommend avoiding routine hуреrvеntilаtion in patients with moderate or severe ΤΒΙ because of safety concerns, especially in the acute phase (the first 24 to 48 hours) following ΤΒI [12]. Mild to moderate hуреrvеոtilаtion to a PaCO2 of 28 to 35 mmHg can be considered as a temporary intervention to help resolve ICP crises; however, a PaCO2 ≤25 mmHg should be avoided [12,84]. (See 'Patients with impending cerebral herniation' below.)