Created at 3:20 p.m. Nov, 01, 2024
Author:
mohannadkh10
Type of change:
Updated content
Rationale for change
PI works in the post-translation part and I am not quite sure how "viral replication" is a correct description
Amboss " inhibition of viral HIV-1 protease (encoded by pol gene) → inability to cleave viral polyproteins into functional units → generation of impaired viral proteins → production of immature (noninfectious) virions"
UW " These drugs reversibly inhibit viral protease, an enzyme responsible for HIV polyprotein cleavage to form mature viral proteins."
Source: AMBOSS - https://next.amboss.com/us/article/mf0V52?q=protease%20inhibitors#Zc6403c5491fd7c32cad8af1523186830
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