Rejected
at 1:09 a.m. Nov, 01, 2023 ]
by
Bilal
Author:
shmuelsash
Type of change:
Other
Rationale for change
Source: https://www.panafrican-med-journal.com/content/article/42/186/full/
Rejection reason
sources. Refer to amboss or uworld
Current
Suggested
Text
Text
Text
Text
Extra
- Desmoglein is a cadherin protein of the desmosome that offers cohesions between keratinocytes


Photo credit: Mohammad2018, CC BY-SA 4.0, via Wikimedia Commons;
Image(s) licensed by DermNet and used with permission, CC-BY-NC-ND 3.0 NZ

Photo credit: Tham et al., CC BY 4.0, via BMC Veterinary Research (1st image); Si et al., CC BY 2.0, via BMC Diagnostic Pathology, modified by brightening, cropping, and removing letter "A"; the supplementary image with overlays of the relevant areas was adapted from the image mentioned previously (© AnkiHub, LLC)

- Inactivation of desmoglein → loss of desmosomes → epidermolysis (especially stratum spinosum) leads to structurally weak blister formation


Photo credit: Mohammad2018, CC BY-SA 4.0, via Wikimedia Commons;
Image(s) licensed by DermNet and used with permission, CC-BY-NC-ND 3.0 NZ

Photo credit: Tham et al., CC BY 4.0, via BMC Veterinary Research (1st image); Si et al., CC BY 2.0, via BMC Diagnostic Pathology, modified by brightening, cropping, and removing letter "A"; the supplementary image with overlays of the relevant areas was adapted from the image mentioned previously (© AnkiHub, LLC)

Lecture Notes
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Missed Questions
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Pathoma
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Boards and Beyond
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First Aid


Sketchy
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Sketchy 2
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Sketchy Extra
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Picmonic
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Pixorize
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Physeo
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Bootcamp
Watch associated Bootcamp video - Inflammatory Diseases of the Skin: Autoimmune Blistering Conditions
Watch associated Bootcamp video - General Principles: Histopathology
Watch associated Bootcamp video - Infectious Dermatologic Disease: Infectious Childhood Rashes (Impetigo, Molluscum, Scarlet Fever)
Watch associated Bootcamp video - General Principles: Histopathology
Watch associated Bootcamp video - Infectious Dermatologic Disease: Infectious Childhood Rashes (Impetigo, Molluscum, Scarlet Fever)
OME
Additional Resources


Atlas:

Desmosomes (desmogleins 1 & 3)


Atlas:

Desmosomes (desmogleins 1 & 3)
versus the basement membrane (hemidesmosomes) targeted in bullous pemphigoid (bullow, below)

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One by one
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