Rejected at 5:30 p.m. Jan, 03, 2025 ] by Brian_BH
Author: williamlee11281
Related Note: 1715982424235
Rationale for change

Early follicular phase: Estradiol has a negative feedback effect on the hypothalamus and anterior pituitary, leading to inhibition of FSH and LH secretion. This helps ensure that only a few follicles develop.

Late follicular phase: As estradiol levels rise significantly due to the growing dominant follicle, it switches to exert a positive feedback effect on the hypothalamus and pituitary. This results in a surge of LH (and to a lesser extent FSH), which triggers ovulation.

Rejection reason

Unresolved unresponded to.

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