Rejected at 7:26 p.m. Oct, 10, 2024 ] by Cameron
Author: amber.go
Related Note: 1509745235242
Rationale for change

I suggest the following card change: "Which azole antifungal is a potent inhibitor of human CYP450?

{{c1::Voriconazole}}"

Reasoning: Voriconazole inhibits cytochrome P450, not the other way around. The way the card is written suggests that cytochrome P450 inhibits voriconazole.

Because voriconazole inhibits cytochrome P450, we need dose reduction of drugs that are metabolized by cytochrome P450 like cyclosporine, warfarin, tacrolimyus, and statins

Rejection reason

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#AK_Step1_v12::#Physeo::^physeo_image_update #AK_Step1_v12::#Bootcamp::Microbiology::37_Antifungals::01_General_Principles_of_Azoles #AK_Step1_v12::#Low/HighYield::3-HighYield-temporary #AK_Step1_v12::#Physeo::09_Pharm::04_Antifungals::02_Azoles #AK_Step1_v12::#Bootcamp::Microbiology::37_Antifungals::02_Azoles #AK_Step1_v12::#UWorld::Step::6481 #AK_Step1_v12::#FirstAid::03_Microbiology::07_Antimicrobials::34_Azoles #AK_Step1_v12::#AMBOSS::xlaE_k #AK_Step1_v12::#SketchyPharm::09_Pharmacology_Foundations::04_Metabolism::01_Introduction_to_CYP450 #AK_Step2_v12::#SketchyIM::08_Hematology_&_Oncology::01_Bleeding_&_Clotting_Disorders::01_Bleeding_Disorders:_Coagulation_Factor_Disorders_DDx #AK_Step1_v12::#Bootcamp::Pharmacology::02_Pharmacokinetics::04_Cytochrome_P450_Interactions #AK_Step1_v12::#NinjaNerd::03_Microbiology::04_Pharmacology::02_Antifungals #AK_Step1_v12::#Bootcamp::Microbiology::18_Opportunistic_Mycosis::02_Aspergillus_Diagnostics_and_Management #AK_Other::#AK_Original_Decks::Step_1::Lolnotacop::Drugs #AK_Step1_v12::#UWorld::Step::18668 #AK_Step1_v12::#OME::PreClinical::Microbiology::Microbiology_4::Fungi::Fungi #AK_Step1_v12::#SketchyPharm::07_Antimicrobials::05_Antifungals::02_Azoles #AK_Step1_v12::#Pixorize::04_Microbiology::02_Antifungals::04_Azoles