Accepted at 11:57 a.m. Dec, 24, 2024 by Ahmed7
Author: gpommier
Related Note: 1488765303577 1
Rationale for change

I propose changing the cloze from "metabolized" to "cytochrome P450" to better reinforce the relationship between warfarin and cytochrome P450. It's basic knowledge that cytochrome P450 metabolizes substrates and thus putting "metabolized" in a cloze doesn't reinforce the key concept of this card.

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Extra
Specifically CYP2C9

Metabolized by P450:
Always-PEDantically Think When Skating Outdoors with Anna
Anti-Psychotics/Epileptics/Depressants
Theophylline
Warfarin
Statins
Oral Contraceptive Pills
Anesthetics
Lecture Notes
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Missed Questions
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Pathoma
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Boards and Beyond
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First Aid
Sketchy

Watch Warfarin

Sketchy 2






Watch Bleeding Disorders: Coagulation Factor Disorders DDx
Sketchy Extra
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Picmonic
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Pixorize


Watch Warfarin
Physeo

Bootcamp
Watch associated Bootcamp video - Vitamin K Dependent Coagulation Factors

Watch associated Bootcamp video - Pharmacokinetics: Cytochrome P450 Interactions

Watch associated Bootcamp video - Antibiotics: Macrolides
OME

Additional Resources
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#AK_Step1_v12::#SketchyPharm::09_Pharmacology_Foundations::04_Metabolism::01_Introduction_to_CYP450 #AK_Step1_v12::#AMBOSS::4ha3V4 #AK_Step1_v12::#FirstAid::10_Hematology_and_Oncology::05_Pharm::02_Warfarin #AK_Step1_v12::#UWorld::Step::6768 #AK_Step1_v12::#AMBOSS::lQavw4 #AK_Step1_v12::#Bootcamp::Hematology_and_Oncology::07_Coagulation_and_Fibrinolysis::09_Vitamin_K_Dependent_Coagulation_Factors #AK_Original_Decks::Step_1::Zanki_Pharmacology #AK_Step1_v12::#Physeo::09_Pharm::17_Hem/Onc_Pharm::03_Warfarin #AK_Step1_v12::#B&B::01_Basic_Pharmacology::01_General::04_Drug_Elimination::Extra #AK_Step2_v12::#SketchyIM::08_Hematology_&_Oncology::01_Bleeding_&_Clotting_Disorders::01_Bleeding_Disorders:_Coagulation_Factor_Disorders_DDx #AK_Step1_v12::#UWorld::#UWSA2 #AK_Step1_v12::^Other::^HighYield::3-HighYield-temporary #AK_Step1_v12::#AMBOSS::xlaE_k #AK_Step1_v12::#Bootcamp::Pharmacology::02_Pharmacokinetics::04_Cytochrome_P450_Interactions #AK_Step2_v12::#AMBOSS::ux0pyR #AK_Step1_v12::#UWorld::Step::6490 #AK_Step1_v12::#UWorld::#UWSA1 #AK_Step1_v12::#SketchyPharm::03_Blood_&_Inflammation::01_Anticoagulants_&_Thrombolytics::02_Warfarin #AK_Step1_v12::#Pixorize::03_Pharmacology::11_Heme_Pharm::01_Warfarin #AK_Step1_v12::#OME::Clinical::Pediatrics::Pediatric_Subspecialties::Pediatric_Seizures #AK_Step1_v12::#Physeo::^physeo_image_update !AK_UpdateTags::Step1decks::Zanki-Pharmacology #AK_Step1_v12::#UWorld::Step::6481 #AK_Step1_v12::#Bootcamp::Microbiology::36_Antibiotics::14_Macrolides #AK_Step2_v12::#AMBOSS