Rejected at 1:04 a.m. Oct, 30, 2024 ] by thomas.holmes
Author: tophamd
Related Note: 1485917673949
Rationale for change

The modifier "if a higher value indicates the presence of the disease" is essential because the behavior of sensitivity and negative predictive value (NPV) when raising the cutoff depends on whether a higher or lower value indicates disease

Higher Value Indicates Disease (e.g., blood glucose for diabetes):

Raising the cutoff: You now require a higher glucose level to diagnose diabetes.
Sensitivity decreases: Fewer people with diabetes will meet the new, higher threshold, increasing false negatives.
NPV decreases: The proportion of true negatives among those who test negative will decrease because more people with diabetes are missed.

Lower Value Indicates Disease (e.g., serum albumin for malnutrition):

Raising the cutoff: You now require a higher albumin level (fewer people would meet the lower threshold).
Sensitivity increases: More people with malnutrition will be detected, reducing false negatives.
NPV increases: With fewer false negatives, the likelihood that a negative result truly indicates no maln
Source: AMBOSS - First Aid Chapt 2.6 or the note in the Anking image in the extra feild

Rejection reason

see comment section, there are many similar cards and they all make this assumption - correct but not necessary as it's implied

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Pathoma
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#AK_Step2_v12::#AMBOSS::ov00aR #AK_Other::#AK_Original_Decks::Step_1::Zanki_Step_Decks::Zanki_Public_Health_Sciences::Epidemiology_&_Biostats #AK_Step1_v12::#FirstAid::06_Public_Health::01_Epidemiology_and_Biostatistics::09_Evaluation_of_diagnostic_tests #AK_Step1_v12::#Physeo::04_Biostatistics::01_Biostatistics::06_Sensitivity_&_Specificity #AK_Step1_v12::#Physeo::04_Biostatistics::01_Biostatistics::07_PPV_&_NPV #AK_Step2_v12::#FirstAid::04_Epidemiology::03_Assessment_of_Diagnostic_Studies::02_Positive_and_Negative_Predictive_Values #AK_Step1_v12::#B&B::05_Biostats/Epi::02_Epidemiology::04_Predictive_Values #AK_Step1_v12::#FirstAid::06_Public_Health::01_Epidemiology_and_Biostatistics::09_Evaluation_of_diagnostic_tests::01_Sensitivity_(true-positive_rate) #AK_Step2_v12::#UWorld::Step::2135 #AK_Step2_v12::#B&B::05_Epidemiology::01_General::07_Sensitivity_and_Specificity::Extra #AK_Step2_v12::#UWorld::Step::7712 #AK_Step2_v12::#AMBOSS::TE06E3 #AK_Step2_v12::#UWorld::Step::6910 #AK_Other::!AK_UpdateTags::AnKing_Image::Mujeeb::Cutoff_Value #AK_Step1_v12::#Bootcamp::Biostatistics::04_Diagnostic_Tests::03_Diagnostic_Test_Thresholds #AK_Step2_v12::#Subjects::Epidemiology_&_Social_Sciences::Biostats::Sensitivity_Specificity_PPV_NPV #AK_Step2_v12::#B&B::05_Epidemiology::01_General::08_Predictive_Values #AK_Step2_v12::#Resources_by_rotation::biostats::dorian::sen_spec_ppv_npv #AK_Step1_v12::#FirstAid::06_Public_Health::01_Epidemiology_and_Biostatistics::09_Evaluation_of_diagnostic_tests::04_Negative_predictive_value #AK_Step2_v12::Original_decks::Dorian::im::biostats::sen_spec_ppv_npv #AK_Step1_v12::#OME_banner #AK_Other::!AK_UpdateTags::AnKing_Image::!Subjects::Epidemiology_&_Social_Sciences::Cutoff_Value #AK_Step2_v12::#UWorld::#UWSA1 #AK_Step1_v12::#Low/HighYield::1-HighYield #AK_Step1_v12::#NBME::30 #AK_Step1_v12::^Systems::Biostats #AK_Step2_v12::#UWorld::COMLEX::27955 #AK_Step2_v12::!Shelf::IM::no_dupes #AK_Step1_v12::#B&B::05_Biostats/Epi::02_Epidemiology::03_Sensitivity_and_Specificity::Extra #AK_Step2_v12::#UWorld::COMLEX::101799