Accepted at 11:06 p.m. Aug, 06, 2024 by TheAnKing
Author: WCStehnach
Related Note: 1649778445164
Rationale for change

Clarity

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Extra
Other inhibitors: metronidazole, protease inhibitors, SSRIs (eg, sertraline), cimetidine, and CCBs

Important examples:
  • Itraconazole given w/ cyclosporine → toxicity
  • Itraconazole given w/ warfarin → ↑ anticoagulant potential/INR
  • Itraconazole given w/ lovastatin → rhabdomyolysis
Note: azithromycin is NOT a CYP3A4 or -1A2 inhibitor like other macrolides

Substrates:
  • Warfarin
  • Carbamazepine
  • Doxepin
  • Sertraline
  • Antidysrhythmics (eg, amiodarone, digoxin, and quinidine)
  • CCBs (eg, diltiazem and nifedipine)
  • Chemotherapy (eg, doxorubicin, vinblastine, and cyclophosphamide)
  • H1 antihistamines
  • HMG CoA reductase inhibitors (eg, lovastatin and simvastatin)
  • OCPs/estrogens
  • Cyclosporine
  • Tacrolimus
  • CS
  • Dapsone
  • Pimozide
  • Benzodiazepines
  • Protease inhibitors
  • Tofacitinib, upadacitinib
  • Colchicine
Personal Notes
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DermPath
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Dermoscopy
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DermNet
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Full Spectrum of Dermatology
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Textbook
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AnkiHub_Subdeck::Dermki::02_Dermatopharmacology #Dermki::Alikhan::02_Dermatopharmacology::02.09_Drug_interactions