Rejected at 2:22 p.m. Dec, 09, 2024 ] by IantheBFG
Author: wangbrian99
Related Note: 1475364123204
Rationale for change

The image made by Anking states that on LM there's GBM thickening. On EM, there's mesangial expansion

Rejection reason

Will update image

Diabetic nephropathy shows mesangial expansion on both LM and EM

Diabetic glomerulonephropathy: light microscopy shows mesangial matrix expansion, thickening of glomerular membrane, and/or nodular eosinophilic glomerulosclerosis (Kimmelstiel-Wilson lesions)
https://next.amboss.com/us/article/Mg0MD2?q=nephrotic+syndrome

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Extra
Non-enzymatic glycation of mesangial cells leads to mesangial expansion and diffuse deposition of type IV collagen leading to glomerular basement thickening and increased permeability

Lecture Notes
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Pathoma
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Boards and Beyond
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First Aid


Sketchy


Watch Nephrotic Syndrome
Sketchy 2

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Picmonic
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Physeo
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Bootcamp
Watch associated Bootcamp video - Diabetic Glomerulonephropathy
OME

Additional Resources

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#AK_Step1_v12::#Pathoma::12_Renal::03_Nephrotic_Syndrome #AK_Step2_v12::#AMBOSS::4aa3kQ !AK_UpdateTags::AnKing_Image::Michael #AK_Step1_v12::^Systems::Renal::Pathology #AK_Step1_v12::#SketchyPath::04_Renal::02_Glomerulopathy::01_Nephrotic_Syndrome !AK_UpdateTags::Step1decks::Zanki-Step-Decks::Zanki-Renal::Renal-Pathology #AK_Original_Decks::Step_1::Zanki_Step_Decks::Zanki_Renal::Renal_Pathology #AK_Step1_v12::#AMBOSS::fbakGQ #AK_Step1_v12::#Bootcamp::Nephrology::08_Nephrotic_Syndromes::06_Diabetic_Glomerulonephropathy #AK_Step1_v12::#Physeo::11_Pathology::02_Endocrine_Pathology::06_Endocrine_Pancreas #AK_Step1_v12::#Physeo::11_Pathology::08_Renal_Pathology::03_Nephrotic_Syndrome #AK_Step1_v12::#OME::PreClinical::04_Organ_Systems::06_Endocrine::05_Pancreas::02_Diabetes #AK_Step1_v12::#AMBOSS::Z6aZjl #AK_Step1_v12::^Other::^HighYield::1-HighYield #AK_Step1_v12::^Other::^FA_Updates::FA2018 #AK_Step2_v12::#SketchyIM::05_Endocrinology::01_Diabetes_Mellitus::03_Chronic_Diabetes_Complications_SOAP #AK_Step2_v12::#B&B::15_Renal_and_Genitourinary::04_Glomerular_Disease::01_Nephrotic_Syndrome #AK_Step1_v12::#AMBOSS::4aa3kQ #AK_Step1_v12::^Other::^EXPN::BGedit #AK_Step1_v12::$AnKingUpdates::$Errata::v12 #AK_Step1_v12::#FirstAid::14_Renal::04_Pathology::05_Nephrotic_syndrome::*Diabetes #AK_Step1_v12::#B&B::08_Endocrinology::03_Pancreas::02_Diabetes #AK_Step1_v12::#OME::04_Organ_Systems::06_Endocrine::05_Pancreas::02_Diabetes