Rejected
at 5:12 p.m. Dec, 15, 2024 ]
by
IantheBFG
Author:
BeefNudels
Type of change:
Content error
Rationale for change
From the AMBOSS add-on for Anki
"The development of a pituitary tumor following bilateral adrenalectomy for refractory Cushing syndrome."
Not explicitly written in the actual AMBOSS article: https://next.amboss.com/us/article/fg0ku2#Y7fa4cc5e0b2f34238875957f7a172597
Rejection reason
change made with another suggestion
Current
Suggested
Text
Text
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Extra
- AKA postadrenalectomy syndrome
- Sudden decrease in cortisol increases ACTH secretion via loss of negative feedback; leads to enlargement of preexisting but undetected pituitary adenoma
- Patient must take glucocorticoid & mineralocorticoids for the rest of their life
1) Indications include primary Cushing syndrome due to bilateral adrenal disease or severe secondary Cushing syndrome refractory to treatment
2) Bilateral adrenalectomy causes sudden drop in cortisol
3) Loss of negative feedback from cortisol
4) Increased corticotropin-releasing hormone (CRH) production
5) Enlargement of preexisting but undetected pituitary adenoma
6) Symptoms manifest (e.g., hyperpigmentation, headaches, & bitemporal hemianopsia)
- Sudden decrease in cortisol increases ACTH secretion via loss of negative feedback; leads to enlargement of preexisting but undetected pituitary adenoma
- Patient must take glucocorticoid & mineralocorticoids for the rest of their life
1) Indications include primary Cushing syndrome due to bilateral adrenal disease or severe secondary Cushing syndrome refractory to treatment
2) Bilateral adrenalectomy causes sudden drop in cortisol
3) Loss of negative feedback from cortisol
4) Increased corticotropin-releasing hormone (CRH) production
5) Enlargement of preexisting but undetected pituitary adenoma
6) Symptoms manifest (e.g., hyperpigmentation, headaches, & bitemporal hemianopsia)
Lecture Notes
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Pathoma
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Boards and Beyond
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First Aid
Sketchy
Sketchy 2
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Sketchy Extra
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Picmonic
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Pixorize
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Bootcamp
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OME
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