Accepted at 7:13 p.m. Jul, 24, 2024 by Ahmed7
Author: pdogg707
Related Note: 1482886567135
Rationale for change

UWorld Question ID 19682 asks cause of Hirschsprung disease

Text
{{c2::Hirschsprung}} disease occurs due to a congenital failure of {{c1::ganglion}} cells to descend into the myenteric and submucosal plexus
Extra
Ganglion cells are derived from the neural crest; neural crest cells moved caudally along vagal nerve fibers, present in wall of proximal colon at 8th week of gestation, and in rectum by 12th week
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#AK_Step1_v12::#UWorld::Step::19682
#AK_Step2_v12::#SketchyPeds::01_Gastroenterology::02_Congenital_GI_Disease::02_Hirschsprung's_Disease_SOAP #AK_Step1_v12::^Other::^HighYield::1-HighYield #AK_Step2_v12::#AMBOSS::VwaG35 #AK_Step1_v12::#Pathoma::10_GI::08_Colon #AK_Step2_v12::#Resources_by_rotation::Peds::step1_pediatrics_zanki #AK_Step1_v12::^Systems::GI::pathology #AK_Step1_v12::#AMBOSS::WgaP8P #PANCE::EOR::PEDS #AK_Original_Decks::Step_1::Zanki_Step_Decks::Zanki_GI::GI_Pathology #AK_Step1_v12::#UWorld::Step::331 #AK_Step1_v12::#B&B::09_GI::03_Clinical::12_Intestinal_Disorders #AK_Step2_v12::#Resources_by_rotation::Surgery::ome::subspecialty::peds_dayweekmonth #AK_Step2_v12::Original_decks::Zanki_Step_2::Peds::Step_1_Pediatrics !AK_UpdateTags::Step1decks::Zanki-Step-Decks::Zanki-GI::GI-Pathology #AK_Step2_v12::#UWorld::COMLEX::28283 #AK_Step2_v12::#B&B::12_Pediatrics::03_Other::04_Congenital_Gastroenterology_I #AK_Step1_v12::#SketchyPath::05_GI::02_Small_Bowel_Disorders::04_Congenital_GI_Disorders #AK_Step1_v12::#UWorld::COMLEX::23444 #AK_Step2_v12::Original_decks::Dorian::surg::ome::subspecialty::peds_dayweekmonth #AK_Step1_v12::#UWorld::COMLEX::23443 #AK_Step1_v12::^Other::^EXPN::Uworld #AK_Step1_v12::^Other::^EXPN::BGedit #AK_Step1_v12::#AMBOSS::mgaVDP #AK_Step1_v12::#UWorld::COMLEX::27178 #PANCE::GI::small_intestine_disorders #AK_Step1_v12::#Physeo::01_Embryology::05_GI::02_Foregut_&_Hindgut_Pathology #AK_Step2_v12::#OME::06_Surgery::03_Surgical_Subspecialties::02_Peds_Weeks_to_Months #AK_Step1_v12::#Physeo::11_Pathology::06_Gastrointestinal_Pathology::08_Diseases_Of_Colon #AK_Step2_v12::#UWorld::Step::2467 #AK_Step2_v12::#AMBOSS::tK0XRS #AK_Step2_v12::#Subjects::Gastroenterology::06_Large_Intestine::Hirschsprung #AK_Step1_v12::#FirstAid::09_Gastrointestinal::04_Pathology::19_Hirschsprung_Disease #AK_Step1_v12::#Physeo::02_Anatomy::04_GI::05_Layers_of_the_Intestinal_Wall #AK_Step2_v12::#OME::03_Pediatrics::03_Failure_to_Pass_Meconium #AK_Step1_v12::#OME::Clinical::Intern_Bootcamp #AK_Step1_v12::#UWorld::Step::19675 #AK_Step1_v12::#UWorld::Step::330 #AK_Step2_v12::!Shelf::Peds::no_dupes #AK_Step1_v12::#Bootcamp::Gastroenterology::09_Colorectal_Pathology::03_Neonatal_Disorders