Created at 2:36 p.m. Jun, 21, 2024
Author:
mohannadkh10
Co-authors:
DillingerMed
Type of change:
Updated content
Rationale for change
Both amboss (link) and UW (table) 2641
Name rasburicase for both prophylaxis and treatment while rasburicase alone for treatment
Amboss text
Indications
Treatment of established TLS
Prophylaxis for intermediate to high-risk patients (low to intermediate risk we use allopurinol)
Source: AMBOSS - https://next.amboss.com/us/article/uJ0pDS?q=tumor%20lysis%20syndrome#-X1D0f0
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Suggested
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- Allopurinol is indicated as prophylaxis via inhibiting uric acid formation, it does NOT influence uric acid breakdown
- Rasburicase is indicated for established hyperuricemia due to TLS via conversion of uric acid to allantoin
- Rasburicase is indicated for established hyperuricemia due to TLS via conversion of uric acid to allantoin
Lecture Notes
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Missed Questions
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Pathoma
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Boards and Beyond
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First Aid






Sketchy Extra
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Picmonic
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Physeo
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Bootcamp
Watch associated Bootcamp video - Plasma Cell Dyscrasias and Myeloproliferative Disease: Tumor Lysis Syndrome
Watch associated Bootcamp video - Non-Rheumatologic Diseases : Gout
Watch associated Bootcamp video - Non-Rheumatologic Diseases : Gout
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Additional Resources
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