Accepted
at 3:33 p.m. Jun, 18, 2024
by
IantheBFG
Type of change:
Updated content
Rationale for change
"Ependymomas are frequently benign with a distinct tumor-spinal cord interface, facilitating gross total resection as a viable option."
https://www.ncbi.nlm.nih.gov/books/NBK442031/
Most are benign. They have the ability to be malignant.
Please read the article and update the card. Even sketchy and AMBOSS do not specify between malignant nor benign because Ependymomas can be both. It depends on the stage of the lesion.
Before
After
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Ependymoma is a(n) {{c1::malignant::benign or malignant}} tumor of {{c2::ependymal cells}}
Lecture Notes
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Missed Questions
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Pathoma
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Boards and Beyond
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First Aid
Sketchy
Watch Pediatric CNS Tumors
Watch Pediatric CNS Tumors
Sketchy 2
Watch Pediatric CNS Tumors
Watch Pediatric CNS Tumors
Sketchy Extra
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Picmonic
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Pixorize
Review Ependymoma
Review Ependymoma
Physeo
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OME
Additional Resources
Atlas:
Ependymal pseudorosette
Photomicrograph of brain tissue (H&E stain)
Tumor cells (cylindrical epithelium) are arranged in a radial manner around several vessels. This pattern is called a perivascular pseudorosette.
Perivascular pseudorosettes are a hallmark of ependymoma.
Ependymoma
Photomicrograph of ependymal tissue (H&E stain)
There is an abnormally high number of cells with round nuclei and abundant cytoplasms. Some cells are arranged in a spoke-and-wheel pattern, surrounding an empty central lumen. Such patterns are called ependymal rosettes (example indicated by green overlay).
Other cells are arranged concentrically around vessels, producing a similar appearance (perivascular pseudorosettes; example indicated yellow overlay).
Other cells are arranged concentrically around vessels, producing a similar appearance (perivascular pseudorosettes; example indicated yellow overlay).
Ependymoma
Cranial MRI (FLAIR-sequence, sagittal view)
A hyperintense, heterogeneous, extended mass is visible on the roof of the 4th ventricle (white outline). At the superior aspect of the tumor, multiple cysts are present (white arrows). As a result of an obstructed circulation of the cerebrospinal fluid, the 3rd ventricle appears widened.
This is a typical radiologic presentation and location of ependymoma.
Atlas:
One by one
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