Accepted
at 5:40 a.m. Jun, 12, 2024
by
Ahmed7
Bulk Suggestion
Bulk ID:
Heminhimdad/06.12.24-05:37AM
Author:
Heminhimdad
Type of change:
New Tags
Rationale for change
The following cards has been tagged based on the (03-adrenal insufficiency) video of (02-adrenal gland) of (4-endocrinology) module of boards and beyond step 2 series
No changes in fields
Text
Autoimmune polyendocrine syndrome type 2 (Schmidt syndrome / APS-2) is characterized by a triad of:
- {{c1::Adrenal insufficiency}}
- {{c2::Autoimmune thyroid disease}}
- {{c3::T1DM}}
- {{c1::Adrenal insufficiency}}
- {{c2::Autoimmune thyroid disease}}
- {{c3::T1DM}}
Extra
- Classically associated with antibodies against adrenal steroid enzymes (e.g., 17α-hydroxylase)
- Other associated conditions include alopecia areata, pernicious anemia, vitiligo, myasthenia gravis, and rheumatoid arthritis
- Other associated conditions include alopecia areata, pernicious anemia, vitiligo, myasthenia gravis, and rheumatoid arthritis
| Autoimmune Polyendocrine Syndromes | ||
| APS-1 | APS-2 | |
|---|---|---|
| Clinical Features | Adrenal insufficency, hypoparathyroidism, chronic mucocutaneous candidiasis, ectodermal dystrophy | Adrenal insufficiency, autoimmune thyroid disease (e.g., Hashimoto or Graves), T1DM |
| Age of Onset | Childhood | Adulthood |
| Genetic Association | AIRE gene mutaton | HLA-DR3/DR-4 |
Lecture Notes
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Missed Questions
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Pathoma
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Boards and Beyond
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First Aid
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Sketchy
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Sketchy 2
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Sketchy Extra
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Picmonic
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Pixorize
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Physeo
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OME
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Additional Resources
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One by one
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