Accepted at 11:22 p.m. Aug, 04, 2024 by Brian_BH
Author: ws1022
Co-authors: Brian_BH
Related Note: 1717173819468
Rationale for change

Inactivated*

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- Therefore, it is no longer expressed.
- The function of a gene can be studied by knocking it out and seeing what happens
- For example, in the chart below, if you knock out (inactivate/delete) the Igf2 gene in female mice, they produce overly large offspring. If you knock out Igf2 in male mice, they produce dwarfs. Thus, you know the Igf2 gene is involved in growth. 


Photo Credit: Arvid Ă…gren and Andrew G. Clark, CC BY 2.5, via Wikimedia Commons
Lecture Notes
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