Accepted at 2:56 a.m. May, 24, 2024 by herstein.jacob
Author: adavis98
Related Note: 1557514244229 1
Rationale for change

Valproate is relatively contraindicated in pregnancy as well.

Per Amboss, "Classic anticonvulsants (especially carbamazepine and sodium valproate!) should be avoided if possible → teratogenic effects"

Per UTD on management of headaches in pregnancy, "Some anticonvulsants, particularly valproate, are teratogenic and should be avoided"

https://www.uptodate.com/contents/headache-during-pregnancy-and-postpartum?search=migraine%20pregnancy&source=search_result&selectedTitle=1%7E150&usage_type=default&display_rank=1#H5
Source: AMBOSS - https://next.amboss.com/us/article/-N0Ddg?q=valproate#Y6ebda8ab82ae249f8a2071a871236417

Extra Extra
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Overview of migraine treatment

Prophylaxis, 1st-line: {{c1::propranolol, topiramate, or valproate::3}}

Prophylaxis, 2nd-line: {{c1::amitriptyline}}

Abortive, mild: {{c2::supportive / NSAIDs::2}}

Abortive, moderate-to-severe: {{c2::triptans, ergots, antiemetics, or CGRP antagonists::4}}
Lecture Notes
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Missed Questions
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Pathoma
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Boards and Beyond
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First Aid
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Sketchy
Sketchy 2






Watch Migraine
Sketchy Extra
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Picmonic
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Pixorize






Physeo
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Bootcamp
Watch associated Bootcamp video - Antiemetics

Watch associated Bootcamp video - Headache: Migraine
OME

Additional Resources
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