Accepted
at 12:41 a.m. Nov, 01, 2023
by
dollajas
Author:
CobrakMD
Type of change:
Updated content
Rationale for change
Indomethacin is indicated in pre term labor at < 32 weeks.
As such these complications are seen in at <32 weeks.
QID uworld - 17429 for reference
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- Decreased production of prostaglandins leads to fetal vasoconstriction and subsequent decreased renal perfusion = oligohydramnios
- Particularly with prolonged administration; therefore, patients typically receive indomethacin for <48 hours
- Oligohydramnios is typically transient and resolves without intervention once the medication is discontinued
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