Rejected
at 7:01 a.m. Aug, 05, 2025 ]
by
yelbardisi
Author:
larchen
Type of change:
Updated content
Rationale for change
The treatment is specifically inhaled nitric oxide because you want vasodilation in the pulmonary vasculature.
I can see people getting questions about this concept wrong if they put oral nitrates and inhaled nitric oxide both as answer choices.
Source: UWorld - Step 2 19467
Rejection reason
already merged thanks!
Current
Suggested
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Extra
- Dilation of pulmonary vasculature → decreased PVR and reduced right-to-left shunting through ductus arteriosus
- Short half-life of nitric oxide limits effects to pulmonary vasculature
- Short half-life of nitric oxide limits effects to pulmonary vasculature
| Diagnosis | Transient tachypnea of the newborn (TTN) | Respiratory distress syndrome | Persistent pulmonary hypertension |
|---|---|---|---|
| Pathophysiology | Alveolar fluid not cleared properly at birth | Alveolar collapse and atelectasis due to lack of surfactant | Right to left shunting due to high pulmonary vascular resistance resulting in hypoxia |
| Clinical features | Tachypnea resolves by day 2 | Respiratory distress (preterm birth) | Tachypnea and cyanosis |
| Chest x-ray | Perihilar linear streaking bilaterally | Ground glass (reticulogranular), air bronchograms, decreased lung volumes | Clear lung fields, decreased pulmonary vascularity |
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