Accepted
at 8:32 p.m. Apr, 10, 2024
by
IantheBFG
Author:
balexfree
Type of change:
Spelling/Grammar
Rationale for change
prevents answering with "estrogen"
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After
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- LH stimulates activity of cholesterol desmolase in theca cells, which converts cholesterol into pregnenolone
- Theca cells make pregnenolone into progesterone (via 3β-hydroxysteroid dehydrogenase) which is secreted
- Theca cells eventually make pregnenolone into androstenedione (steroid synthesis pathway) which diffuses into nearby granulosa cells
- Granulosa cells convert androstenedione → testosterone (via 17β-hydroxysteroid dehydrogenase) → 17β-estradiol (via aromatase)
- FSH stimulates aromatase
- Theca cells make pregnenolone into progesterone (via 3β-hydroxysteroid dehydrogenase) which is secreted
- Theca cells eventually make pregnenolone into androstenedione (steroid synthesis pathway) which diffuses into nearby granulosa cells
- Granulosa cells convert androstenedione → testosterone (via 17β-hydroxysteroid dehydrogenase) → 17β-estradiol (via aromatase)
- FSH stimulates aromatase
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