Accepted at 3:19 p.m. Mar, 18, 2024 by Cameron
Author: IantheBFG
Co-authors: herstein.jacob , Cameron
Related Note: 1462326961450 1
Rationale for change

This card is wrong due to what older version of first aid used to say. I think this card should stay (but with these changes) because it is the only card that mentions anti-GAD antibodies in the AnKing deck which is important.

First Aid 2023 states it is NOT due to autoantibodies and it's "Autoimmune T-cell–mediated destruction of β cells"

AMBOSS supports this
https://next.amboss.com/us/article/3g0SE2?q=t1dm#Y301e65917280ae965b5c05d31d2b6c46

Other AnKing cards support this as well
nid:1462326990404
"What type of hypersensitivity is type 1 diabetes mellitus?

Type IV HSR (direct cell cytotoxicity)"


This card half supports it but that's because the other half is incorrect. I will submit a change to it as well.
nid:1584129194060
"Type 1 DM is caused by autoimmune destruction of β cells by CD8+ T cells and autoantibodies produced by B cells"

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#AK_Step2_v12::#FirstAid::03_Endocrinology::01_Disorders_of_Glucose_Metabolism::02_Diabetes_Mellitus #AK_Step1_v12::#Physeo::11_Pathology::02_Endocrine_Pathology::06_Endocrine_Pancreas #AK_Step2_v12::#UWorld::Step::3548 #AK_Step1_v12::#Low/HighYield::1-HighYield #AK_Other::!AK_UpdateTags::AnKing_Image::Mujeeb::Diabetes_mellitus #AK_Step2_v12::#B&B::04_Endocrinology::03_Diabetes::02_Diabetes_Complications #AK_Step1_v12::#AMBOSS::YWanPj #AK_Step1_v12::#FirstAid::02_Immunology::03_Immune_Responses::15_Autoantibodies #AK_Step1_v12::#FirstAid::08_Endocrine::04_Pathology::16_Type_1_vs_type_2_diabetes_mellitus::*Type_1 #AK_Step1_v12::#OME::04_Organ_Systems::06_Endocrine::05_Pancreas::02_Diabetes #AK_Step2_v12::#UWorld::COMLEX::100349 #AK_Step2_v12::#SketchyIM::05_Endocrinology::01_Diabetes_Mellitus::01_Diabetes_SOAP #AK_Step1_v12::#Physeo::03_Physiology::06_Endocrinology::06_Diabetes #AK_Step1_v12::#FirstAid::08_Endocrine::04_Pathology::15_Diabetes_mellitus::*Type_1 #AK_Step1_v12::#Pathoma::15_Endocrine::09_Endocrine_Pancreas #AK_Step1_v12::#B&B::09_Endocrinology::03_Pancreas::03_Type_I_Diabetes #AK_Step1_v12::#SketchyPath::07_Endocrine::03_Diabetes::01_Diabetes_Mellitus:_Pathogenesis_&_Acute_Clinical_Manifestations #AK_Step1_v12::#Bootcamp::Endocrinology::07_Pancreas::04_Diabetes_Type_1_and_Type_2 #AK_Step1_v12::!FLAG_THESE_CARDS::Temporary #AK_Step2_v12::#AMBOSS::kp0mpS #AK_Step1_v12::^Systems::Endocrine::Pathology #AK_Other::!AK_UpdateTags::AnKing_Image::!Subjects::Endocrinology::Diabetes_mellitus #AK_Other::#AK_Original_Decks::Step_1::Zanki_Step_Decks::Zanki_Endocrine::Endocrine_Pathology #AK_Step1_v12::#OME::PreClinical::04_Organ_Systems::06_Endocrine::05_Pancreas::02_Diabetes #AK_Step1_v12::#AMBOSS::u5apNO