Rejected at 8:53 p.m. May, 25, 2024 ] by Ahmed7
Author: apeleg
Co-authors: Ahmed7
Related Note: 1514431768534
Rationale for change

This is not true. The elevated risk of AIN is special to Methicillin (no longer in use precisely for this reason), not anti-staphylococcal penicillins as a group.

AMBOSS lists AIN as an adverse effect of all the beta-lactams, noting only methicillin as especially associated with it (https://next.amboss.com/us/article/mm0VTg#Y6b3413c96a064eefa8f8fee0b1104adb). Under AIN, AMBOSS lists a variety of drug classes as causes without specifying any group (https://next.amboss.com/us/article/Jg0sw2?q=acute%20interstitial%20nephritis#FTcgsb0). The source which AMBOSS cites for their AIN page states that Amoxicillin and Ciprofloxacin are the antibiotics associated most with AIN in todays practice.

I think this question should either be removed, or replaced with something more along the lines of "Historically, which modified penicillin antibiotic (rather than group) was especially associated with AIN?"

Rejection reason

Real-life and boards can be different and that's okay. sticking to FA24 (see comments)

Text Text
Extra
- AKA the penicillinase-resistant penicillins
- AIN can be asymptomatic, but is associated with pyuria + hematuria, fever, and rash
Lecture Notes
Empty field
Missed Questions
Empty field
Pathoma
Empty field
Boards and Beyond
Empty field
First Aid
Sketchy



Watch Penicillin
Sketchy 2



Watch Intra-Renal AKI
Sketchy Extra
Empty field
Picmonic
Empty field
Pixorize
Empty field
Physeo

Bootcamp
Watch associated Bootcamp video - Acute Interstitial Nephritis
OME

Additional Resources
Empty field
One by one
Empty field
#AK_Step1_v12::^Other::^FA_Updates::FA2018 #AK_Step1_v12::^Other::^HighYield::4-LowerYield #AK_Step2_v12::#B&B::08_Infectious_Disease::01_Antibiotics::01_Penicillins::Extra #PANCE::RENAL::AKI_and_acute_renal_failure #PANCE::EOR::Family_med AnkiHub_ImageReady::Extra #AK_Original_Decks::Step_1::Zanki_Pharmacology #AK_Step1_v12::^Other::^EXPN #AK_Step1_v12::#Physeo::09_Pharm::05_Antibiotics::02_Amoxicillin_&_Ampicillin #AK_Step1_v12::#Bootcamp::Nephrology::12_Kidney_Injury::06_Acute_Interstitial_Nephritis #AK_Step2_v12::#SketchyIM::04_Nephrology_&_Urology::02_Acute_Kidney_Injury::04_Intra-Renal_AKI #AK_Step1_v12::#OME::Clinical::Internal_Medicine::Infectious_Disease #AK_Step1_v12::#FirstAid::03_Microbiology::07_Antimicrobials::04_Penicillinase-resistant_penicillins !AK_UpdateTags::Step1decks::Zanki-Pharmacology !AK_UpdateTags::^temporary::ImageFix::14::done AnkiHub_ImageReady::Text #AK_Step1_v12::#SketchyPharm::07_Antimicrobials::01_Cell_Wall_&_Membrane-Active_Antibiotics::03_Ampicillin,_Amoxicillin,_Piperacillin,_Ticarcillin::zanki_extra #AK_Step1_v12::#Physeo::^physeo_image_update #AK_Step1_v12::#B&B::19_Renal::04_Diseases_of_the_Nephron::05_Tubulointerstitial_Disease