Accepted at 6:34 p.m. Feb, 10, 2024 by TheAnKing
Author: Tothemoon
Related Note: 1677077611168
Rationale for change

SagisDx dermpath photo

DermPath DermPath
DermNet DermNet
Text
For necrobiosis lipoidica diabeticorum, histology reveals "{{c1::square biopsy}}" sign
Extra
Other histologic findings:
  • Horizontally arranged ("layered") palisaded granulomatous inflammation with horizontal tiers of degenerated collagen fibers (irregular size and shape) and dermal sclerosis
  • Process diffusely involves entire dermis and subQ fat septae (vs. GA, which tends to have patchy, predominantly superficial dermal inflammation)
  • Lacks mucin
  • Plasma cells and multinucleated GCs are abundant (both uncommon in GA)
  • +/- epidermal atrophy; +/- vascular hyalinization
Personal Notes
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Missed Questions
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Dermoscopy
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VisualDx
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Full Spectrum of Dermatology
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Textbook
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One by one
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#Dermki::Alikhan::03_General_Derm::03.06_Granulomatous/histiocytic_disorders AnkiHub_Subdeck::Dermki::03_General_Dermatology