Rejected at 12:23 a.m. Nov, 01, 2023 ] by dollajas
Author: AndrewContreras
Related Note: 1462932277681 1
Rationale for change

Per the image of AIS on Uworld 3911, the patient will have cryptorchid testes which produce testosterone that becomes aromatized to estrogen leading to breast development in AIS patients.

https://imgur.com/a/nIJ4STp

Rejection reason

resolved

Text Text
Extra
- i.e., the presence of the lower vagina, clitoris, and labia, as well as testes

- Testes are often cryptorchid, other male internal genitalia are missing

- Looks like 5α-reductase, but breasts are present due to lack of androgen receptors causing elevated testosterone

- Elevated testosterone is unable to inhibit breast development and is aromatized to estrogen

Lecture Notes
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Missed Questions
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Pathoma
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Boards and Beyond
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First Aid

Sketchy
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Sketchy 2

Watch Primary Amenorrhea DDx
Sketchy Extra
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Picmonic
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Pixorize
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Physeo
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Bootcamp
Watch associated Bootcamp video - Fetal Development: Disorders of Sexual Development Part 1

Watch associated Bootcamp video - Pregnancy and Menstruation: Menstrual Cycle Disorders
OME

Additional Resources
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One by one
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#AK_Step1_v12::#Bootcamp::Reproduction::02_Pregnancy_and_Menstruation::04_Menstrual_Cycle_Disorders #PANCE::EOR::WOMENS_HEALTH #AK_Step2_v12::#AMBOSS::R60lkS #AK_Step1_v12::#B&B::08_Endocrinology::04_Repro::03_Male_Reproductive_Hormones #AK_Step2_v12::#Subjects::Obstetrics_&_Gynecology::03_Pediatrics::01_Embryology::Sexual_Development_Disorders::Androgen_Insensitivity_Syndrome #AK_Step2_v12::#UWorld::Step::15222 #AK_Step2_v12::!Shelf::ObGyn #AK_Step2_v12::#UWorld::COMLEX::102846 #AK_Step1_v12::^Systems::Reproductive::Physiology #AK_Step1_v12::#FirstAid::15_Repro::04_Pathology::06_Androgen_insensitivity_syndrome #AK_Step2_v12::#UWorld::Step::3913 #AK_Step2_v12::Original_decks::Dorian::peds::uw::repro #AK_Step1_v12::#Bootcamp::Reproduction::01_Fetal_Development::08_Disorders_of_Sexual_Development_Part_1 #AK_Step2_v12::#AMBOSS::k60mOS #AK_Step1_v12::#OME::Clinical::Ob/Gyn::Gynecology:_Reproductive_Endocrinology::Primary_Amenorrhea #AK_Step1_v12::#UWorld::Step::6455 #AK_Step2_v12::#Resources_by_rotation::Peds::uworld::repro::repro_dorian #AK_Step2_v12::!Shelf::Peds #AK_Step1_v12::#NBME::Free120 #AK_Step1_v12::#NBME::30 #AK_Original_Decks::Step_1::Zanki_Step_Decks::Zanki_Reproductive::Reproductive_Physiology_+_Anatomy/Embryo #AK_Step2_v12::#UWorld::COMLEX::100705 #AK_Step1_v12::#Costanzo::Repro::01_Sexual_Differentiation #PANCE::REPRODUCTIVE::bleeding_disorders #AK_Step2_v12::#SketchyOBGYN::06_Reproductive_Endocrinology_&_Infertility::01_Reproductive_Endocrinology::02_Primary_Amenorrhea_DDx #AK_Step1_v12::#FirstAid::15_Repro::01_Embryology::17_Genital_embryology #AK_Step1_v12::#NBME::21 #AK_Step2_v12::#OME::05_Obstetrics_and_Gynecology::01_Gynecology::03_Reproductive_Endocrinology::02_Primary_Amenorrhea #AK_Step2_v12::!Shelf::Peds::no_dupes #AK_Step2_v12::#Resources_by_rotation::ObGyn::uw::zanki::female_repro_breast !AK_UpdateTags::Step1decks::Zanki-Step-Decks::Zanki-Reproductive::Reproductive-Physiology+Anatomy/Embryo #AK_Step1_v12::#B&B::20_Repro::07_Other::01_Disorders_of_Sexual_Development #AK_Step2_v12::Original_decks::Zanki_Step_2::Peds::Repro #AK_Step3_v12::#UWorld::5338 #AK_Step2_v12::#B&B::11_Obstetrics_and_Gynecology::02_Gynecology::03_Primary_Amenorrhea #AK_Step2_v12::#Resources_by_rotation::Peds::uworld::repro::repro_zanki #AK_Step1_v12::#UWorld::#UWSA1 #AK_Step1_v12::#AMBOSS::iaaJ4Q !AK_UpdateTags::AnKing_Image::Mujeeb::Primary_Amenorrhea #AK_Step1_v12::$AnKingUpdates::$Errata::v12