Accepted at 12:22 a.m. Nov, 01, 2023 by Alex
Author: ZigWiggy
Related Note: 1481335888586
Rationale for change

multiple myeloma doesn't get deposited in tissue, the free light chain the overabundant plasma cells produce does.

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Extra
- MultipAL myeloma
- Free light chains (overproduced in MM) circulate in serum and deposit in tissue as amyloid light chain (AL)
- May present as restrictive cardiomyopathy (HFpEF) and glossitis (sleep apnea)

Lecture Notes
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Missed Questions
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Pathoma
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Boards and Beyond
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First Aid

Sketchy 2
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Sketchy Extra
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Picmonic
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Physeo
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OME

Additional Resources

Atlas:

Other:
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#AK_Step2_v12::#Resources_by_rotation::IM::ome::heme/onc::plasma_cell #AK_Step1_v12::#FirstAid::04_Pathology::01_Cellular_Injury::11_Amyloidosis::01_Systemic::*Primary_Amyloidosis #AK_Step2_v12::Original_decks::Dorian::im::ome::heme/onc::plasma_cell #AK_Step1_v12::#SketchyPath::11_Immunology::01_Autoimmune_&_Amyloidosis::04_Amyloidosis #AK_Step2_v12::#AMBOSS::BF0z43 #AK_Step1_v12::^Systems::HemeOnc::WBC #AK_Step2_v12::#OME::05_Heme_Onc::07_Plasma_Cell #AK_Step2_v12::#B&B::07_Hematology_and_Oncology::03_White_Cells::07_Amyloidosis #AK_Step1_v12::#B&B::11_Hematology::03_White_Blood_Cells::05_Plasma_Cell_Disorders::Extra #AK_Step1_v12::#OME::13_Hematology_Oncology::04_Proliferation::05_Plasma_Cell_Dyscrasis #AK_Step1_v12::#FirstAid::04_Pathology::01_Cellular_Injury::11_Amyloidosis #AK_Step1_v12::#Physeo::11_Pathology::10_HemeOnc_Pathology::18_Plasma_Cell_Dyscrasias #AK_Step1_v12::#NBME::18 #AK_Step1_v12::#AMBOSS::SbayGQ #AK_Step1_v12::#FirstAid::10_Hematology_and_Oncology::04_Pathology::26_Plasma_cell_dyscrasias::01_Multiple_myeloma #AK_Step1_v12::^Other::^HighYield::1-HighYield #AK_Step1_v12::#OME::PreClinical::13_Hematology_Oncology::04_Proliferation::05_Plasma_Cell_Dyscrasis #AK_Step1_v12::#Bootcamp::Nephrology::08_Nephrotic_Syndromes::05_Amyloid_Nephropathy #AK_Step1_v12::#Bootcamp::Hematology_and_Oncology::10_Plasma_Cell_Dyscrasias_&_Myeloproliferative_Disease::01_Multiple_Myeloma #AK_Original_Decks::Step_1::Zanki_Step_Decks::Zanki_Hematology_&_Oncology::Pathoma_WBC #AK_Step1_v12::#SketchyPath::10_Myeloid_&_Lymphoid::02_Lymphoid_&_Plasma_Cell_Disorders::04_Plasma_Cell_Neoplasms !AK_UpdateTags::AnKing_Image::Mujeeb::Amyloidosis #AK_Step1_v12::#AMBOSS::yWadLj #AK_Step1_v12::#UWorld::Step::872 #AK_Step1_v12::#UWorld::COMLEX::23984 #AK_Step1_v12::#Pixorize::01_Biochemistry::19_Plasma_Cell_Dyscrasias::02_Multiple_Myeloma #AK_Step1_v12::#Physeo::11_Pathology::07_General_Pathology::06_Amyloidosis #AK_Step2_v12::#AMBOSS::xF0E43 #AK_Step2_v12::!Shelf::IM::no_dupes !AK_UpdateTags::Step1decks::Zanki-Step-Decks::Zanki-Hematology-&-Oncology::Pathoma-WBC #AK_Step1_v12::#Pathoma::06_WBC::08_Plasma_Cell_(Dyscrasias) #AK_Step1_v12::#FirstAid::10_Hematology_and_Oncology::04_Pathology::26_Plasma_cell_dyscrasias