Accepted at 12:21 a.m. Nov, 01, 2023 by dollajas
Author: jprasadh
Related Note: 1489968541246
Rationale for change

cloze 2 needs a hint ::2, since two different cytokines are being asked. Cloze 1 doesn't need the hint ::2, in my opinion, since if you recall psoriasis as an indication, you'll also likely recall psoriatic arthritis

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- IL-12 stimulates TH1 cells, IL-23 leads to stimulation of gamma-delta T cells

- IL-23 stimulates Th17 cells which leads to Crohn, UC, and psoriasis/psoriatic arthritis. IL-23 also leads to stimulation of gamma-delta T cells which is important for the development of psoriatic arthritis.

- Newly approved treatment for UC. IL-23 is considered the central cytokine in Crohn and possibly UC (blocked by tildrakizumab)
Lecture Notes
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Missed Questions
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Pathoma
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Boards and Beyond
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First Aid
Sketchy
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Sketchy 2

Watch Seronegative Spondyloarthritis DDx
Sketchy Extra
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Picmonic
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Pixorize
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Physeo
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Bootcamp
Watch associated Bootcamp video - Transplant Rejection: Biologic Immunotherapy

Watch associated Bootcamp video - Psoriatic Arthritis

Watch associated Bootcamp video - Inflammatory Disease of the Skin: Red Plaque Disease

Watch associated Bootcamp video - Pharmacology : TNF-a Inhibitors and Monoclonal Antibodies
OME

Additional Resources
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One by one
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#AK_Step1_v12::#OME::PreClinical::Immunology !AK_UpdateTags::Step1decks::Zanki-Pharmacology #AK_Step1_v12::^Other::^HighYield::2-RelativelyHighYield #AK_Step1_v12::#Bootcamp::Dermatology::03_Inflammatory_Diseases_of_the_Skin::05_Red_Plaque_Disease #AK_Original_Decks::Step_1::Zanki_Pharmacology #AK_Step1_v12::#SketchyPharm::Immunology-&-Biochemistry-Pharmacology::Immuno-suppressives::General-Immunotherapy #AK_Step1_v12::^Other::^EXPN #AK_Step1_v12::#Bootcamp::Musculoskeletal::15_Pharmacology::07_TNF_Alpha_Inhibitors_And_Monoclonal_Antibodies #AK_Step1_v12::#FirstAid::02_Immunology::04_Immunosuppressants::03_Therapeutic_antibodies::01_Autoimmune_disease_therapy::*Ustekinumab #AK_Step1_v12::#Bootcamp::Musculoskeletal::04_Seronegative_Spondyloarthritis::02_Psoriatic_Arthritis #AK_Step2_v12::#SketchyIM::07_Rheumatology::04_Seronegative_DIsorders::01_Seronegative_Spondyloarthritis_DDx #AK_Step1_v12::#Bootcamp::Immunology::13_Transplant_Rejection::08_Biologic_Immunotherapy #AK_Step1_v12::#FirstAid::02_Immunology::04_Immunosuppressants::03_Therapeutic_antibodies